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Garcinia Cambogia Supplement Can Be Toxic

Garcinia Cambogia Garcinia Cambogia is being sold in supplement form and is being touted as a weight loss miracle. It reportedly can help people lose a good deal of weight over a short period of time. Used with caution, it can provide impressive results, but as with any weight loss supplement, garcinia cambogia can be dangerous if used improperly. In fact, it can be toxic in some cases. It is specifically problematic when used with antidepressants.

A study was published in the April edition of the Journal of Medical Toxicology detailing the risk of serotonin toxicity associated with the combined use of garcinia cambogia and antidepressants. The weight loss supplement has shown to be toxic for those taking an antidepressant, which results in an abnormally high level of serotonin.

Dr. Robert Hendrickson, from the Department of Emergency Medicine of Oregon Health and Science University, is a toxicologist who confirmed that the combination of antidepressants that are designed to raise the feel good hormone serotonin levels with the garcinia cambogia supplement that also works to increase serotonin. The result is too much of a good thing. Serotonin toxicity may involve muscle spams, stuttering, excessive sweating, confusion, nausea, diarrhea, a rapid heartbeat and high blood pressure. Though serotonin is naturally produced by the brain and is a necessary hormone, too much of it can actually be fatal.

Due to the fact that supplements are not regulated by the FDA the same way that tradition prescription medicines are, there is no way to tell if a person is actually consuming the ingredients listed on the bottle’s label or some other medication or filler. These other ingredients may also interfere with prescription medicines and lead to toxicity.

Garcinia cambogia is a small round fruit that is shaped like a pumpkin. The rind of the fruit contains hydroxycitric acid and it is used to prevent fat storage. It is known to help people feel full longer so they do not overeat and it promotes lean muscle mass, which also helps burn fat and transform how the body looks. Because the supplement contains serotonin, it also helps improve mood, thus curbing the need for emotional eating. The extract gained national attention in 2012 when Dr. Oz brought discussed its benefits on one of his shows.

Though the weight loss supplement can cause nausea and headaches, according to WebMD, it is deemed safe for the most part, as long as it is taken as directed. It is recommended for short-term use for up to 12 weeks. It is not recommended for pregnant women and there has not been a definitive study that proves its effectiveness.

More research is needed to determine if the toxic level of serotonin is actually due to the combination of garcinia cambogia and antidepressants or if a particular antidepressant is responsible for the toxicity. Meanwhile, Dr. Hendrickson states that he is hesitant to label the weight loss supplement as “dangerous,” but it should be used with caution, especially when used along with prescription drugs. It is important to report the use of garcinia cambogia to the physician responsible for administering prescription drugs to avoid possible interactions and toxic levels of serotonin.

By Tracy Rose

Sources:

Journal of Medical Toxicology
Yahoo News
WebMD
Huffington Post

Garcinia Cambogia Supplement Can Be Toxic added by on April 29, 2014
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Weight loss: Follow this #Number1 weight loss advice that experts swear by to lose weight

When it comes to losing weight, it is not the actual process which is overwhelming but the host of ‘nuanced advises’ that are showered from the ‘weight-loss experts’ themselves. From weird diets to exercises that promise to burn those stubborn calories, there is no dearth of information on weight loss.

However, you need to understand that nothing miraculous is going to happen in the first week itself. So don’t go weighing yourself after every workout session as keeping a track of what the scale says may just only demotivate you. Instead, be realistic about the whole journey and understand that it may take anywhere around 4 to 6 weeks to see tangible results.

Secondly, before you go completely overboard with extreme diets and crazy workout sessions, you need to know about that one simple trick that can actually do wonders to aid your quest to lose weight.

If you bite it, write it

It does not matter which diet you choose to follow, as long as you maintain a food log. Yes, the simple habit of jotting down everything you drink and eat can do miracles.

When you write down every single thing that you put inside your mouth–from those 5 o’clock snacks to the chips you had while commuting–it makes you more mindful of what you are eating.

It is also the simplest way to count calories and ensures that you do not exceed your daily calorie intake.

While we suggest going old school by actually carrying a tiny diary and pen with you, wherever you go, you can always make use of the several note pad applications in your smartphone to maintain a regular food log.

The bottom line


If you write down every bite you take, it will make you more mindful of all the extra calories you consume without even realising.

Do keep in mind that you need to jot down everything you eat through the day– which includes those two french fries that you borrowed from your colleague’s lunch. This is the only foolproof way of counting calories and staying true to your goal to lose weight.

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Weight Loss Products

Garcinia Cambogia Extract Blocks Fat, Suppresses Appetite: Ancient Herbal Diet Could Be Next Big Thing

The search for and discovery of a natural diet product, with all its connotations of safety and purity and well, naturalness, should be expected. After all, for many people, weight loss is both a necessity and an obsession. So when Oprah-spinoff Dr. Oz recently publicized garcinia cambogia extract as a supplement that could hasten weight loss efforts, many dieters snapped it up immediately.

The herbal product is extracted from the dried fruit rind of garcinia cambogia, also known as Malabar tamarind, which is a source of hydroxycitric acid (HCA). Although sour in taste, HCA has been used for centuries by Southeastern Asian cooks to make dishes, in particular curries and chutneys, more filling. Tamarind, a small, pumpkin-shaped fruit, is native to Indonesia and also grown in India, Southeast Asia, and West and Central Africa. The fruit is sometimes used to cure fish as well as to preserve foods.

Researchers claim that HCA can double or triple one’s weight loss without stimulating the central nervous system. In other words, garcinia cambogia extract is a kind of anti-ephedra. Dr. Oz recommends the herbal supplement for emotional eaters. He noted that those who participated in a particular study showed increased serotonin levels so the product may also improve mood and sleeping patterns.

How It Works

The HCA extract not only helps to block fat, but also suppresses the appetite.

Essentially, it stops the body from producing fat cells by inhibiting an enzyme, citrate lyase, that your body requires to convert fat from carbohydrates. Usually carbohydrates or sugars are not immediately used or stored turn into fats. When HCA inhibits citrate lyase, the process is interrupted and the production of LDL (bad cholesterol) as well as triglycerides decrease. In cell studies, the extract is shown to inhibit the cytoplasmic lipid accumulation and adipogenic differentiation of preadipocytes.

HCA also suppresses appetite by increasing levels of serotonin, a neurotransmitter in the brain that makes you feel good. It is believed that low levels of serotonin compel people to eat reactively (emotionally); in fact, because low levels of serotonin may make you feel depressed or anxious, serotonin is the target of many antidepressant medications. By increasing serotonin levels, HCA improves mood and suppresses the drive to react to stressful situations with food. As you eat less, your body releases stored fat in your fat cells.

One randomized placebo-controlled study, referred to by Dr. Oz, followed 60 obese persons for eight weeks. Sticking to a calorie-restricted diet (1200 kcal/day) and taking a dose of 1320 mg of HCA each day, the experimental group lost an average of 14 lbs., outdoing the placebo group who, on average, lost a mere 6.1 lbs. Participants in this study also reported reduced appetites.

Recommended Use

Although considered generally safe, this herbal supplement should not be taken by those who are pregnant or breastfeeding, those who are taking a diabetic medication (like insulin or glyburide), those who are taking a statin (cholesterol-lowering drug), and those who have been diagnosed with Alzheimer’s disease or other forms of dementia.

The list of ingredients in whatever product you buy should be reviewed so as to avoid fillers and artificial ingredients. Dr. Oz reports that experts believe newly available HCA potassium salts are more effective than the other formulations. A dieter should take 500-1,000 mg before each meal, without taking more than 3,000 mg total per day. With no other changes to your diet or exercise routine, you may lose 2 to 4 lbs. within one month.

Side Effects

According to Zhion, garcinia cambogia did not show serious side effects in some animal studies. For instance, one study involving rats treated for a period of 90 days showed HCA results in a reduction in body weight, but did not cause any side effects of hepatic and testicular lipid peroxidation, DNA fragmentation, or histopathological changes. Another study of rats found that administration of HCA-SX (dosages up to 2,500 mg/kg/day) for a period of 90 days caused a significant decrease in body weight and reduction in feed consumption without any serious side effects.

Not all studies proved HCA innocuous, though. One study of male Zucker obese rats found that high dosages of garcinia cambogia extract caused potent testicular atrophy and toxicity.

Additionally, some dieters have reported these side effects when using garcinia cambogia extract:

  •  Mild nausea
  •  Digestive tract discomfort and/or more frequent bowel movements
  •  Mild headaches and/or dizziness

As with any untested product, it is recommended dieters consult with their doctors before use. Although garcinia cambogia extract is natural and considered safe, the possibility of frequent bowel movements may not be the kind of weight loss you have in mind.

 

Source: Márquez F, Babio N, Bulló M, Salas-Salvadó J. Evaluation of the safety and efficacy of hydroxycitric acid or Garcinia cambogia extracts in humans. Critical Reviews in Food Science and Nutrition. 2012.