Q: I’m taking the serotonin-reuptake inhibitor sertraline (Zoloft) for depression. I feel so much better, and I assumed it was OK to keep taking my vitamins. But are there supplements I should watch out for?
— Cecilia H., Ossining, New York
A: Congrats on taking charge of your depression and feeling better. Yes, there are certain supplements that interfere with selective serotonin-reuptake inhibitors (SSRIs), and with serotonin and noradrenalin reuptake inhibitors (SNRIs) too.
Serotonin is a neurotransmitter found in your gut, your blood and your nervous system. It’s considered a natural mood stabilizer. You probably weren’t getting the right balance, and the sertraline has helped you re-establish that! Since we don’t know your exact dosage or the supplements you are taking, we can’t directly answer your question. You should talk to your doctor about all the supplements and herbal preparations you may be using. When you do, here are some specifics to discuss: